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SOD2 deficiency resulted in mitochondrial dysfunction and cellular senescence in the epidermis, as well as epidermal thinning, a known feature of aging skin. [8] What this means is you get an increased thickness of the stratum corneum and thinning in the epidermis

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CJC-1295 (no DAC) is a tetra-substituted analog of GRF(1-29) that engages the GHRH receptor on anterior-pituitary cells, while Ipamorelin is a pentapeptide agonist of the ghrelin / growth-hormone-secretagogue receptor (GHS-R1a)